Activity record

PGDB_A044758

Assay: % DegradationQC: ambiguous
Activity overview

degradation = 0 %

Cell lineprimary human PBMC
ConcentrationConcentration context: titrated doses
Time24 h
Assay / Readoutflow_cytometry / % Degradation
Assay IDPGDB_AS001028
PatentWO2025049840
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007373
Compound IDPGDB_C007373
CompoundComparative Compound B
Source record IDPGDB_C007373
InChIKeyVACYFJWFXFNBTI-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001028
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Technologyflow_cytometry
ConcentrationConcentration context: titrated doses
Treatment time24 h
TargetIKZF3
E3Not specified
Cell lineprimary human PBMC
OrganismHomo sapiens

Source evidence

Patent IDWO2025049840
Compound location

Comparative Compound B

Comparative Compound B enlarged structureComparative Compound B location on patent page 101
Activity table
Page 110 · table single