PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

7 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

TargetIKZF3

E3Not specified

Cell lineprimary human PBMC

OrganismHomo sapiens

Technologyflow_cytometry

Activity compounds and values

7 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	=	67	%	Concentration context: titrated doses	24 h	-	-	primary human PBMC	WO2025049840	PGDB_A008684	PGDB_C010127	PGDB_AS001028	View
% Degradation	-	=	58	%	Concentration context: titrated doses	24 h	-	-	primary human PBMC	WO2025049840	PGDB_A017639	PGDB_C010126	PGDB_AS001028	View
% Degradation	-	=	77	%	Concentration context: titrated doses	24 h	-	-	primary human PBMC	WO2025049840	PGDB_A018488	PGDB_C010128	PGDB_AS001028	View
% Degradation	-	=	76	%	Concentration context: titrated doses	24 h	-	-	primary human PBMC	WO2025049840	PGDB_A037494	PGDB_C010125	PGDB_AS001028	View
% Degradation	-	=	0	%	Concentration context: titrated doses	24 h	-	-	primary human PBMC	WO2025049840	PGDB_A044758	PGDB_C007373	PGDB_AS001028	View
% Degradation	-	=	80	%	Concentration context: titrated doses	24 h	-	-	primary human PBMC	WO2025049840	PGDB_A053490	PGDB_C007372	PGDB_AS001028	View
% Degradation	-	=	72	%	Concentration context: titrated doses	24 h	-	-	primary human PBMC	WO2025049840	PGDB_A054638	PGDB_C010129	PGDB_AS001028	View

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