Activity record

PGDB_A045275

Assay: viabilityTarget: KRASQC: standardized
Activity overview

IC50 = 0.4719 nM

TargetKRAS
Cell lineNCI-H358
Time5 d
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS002403
PatentCN121181579A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024627
Compound IDPGDB_C024627
Compound实施例84
Source record IDPGDB_C024627
InChIKeyLZSYLLOZUNKBRZ-DMLMQIDSSA-N

Assay context

Assay IDPGDB_AS002403
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time5 d
Detection targetcell_proliferation
TargetKRAS
E3Not specified
Cell lineNCI-H358
OrganismHomo sapiens

Source evidence

Patent IDCN121181579A
Compound location

实施例84

实施例84 enlarged structure实施例84 location on patent page 31
Activity table
Page 146 · table single