Activity record

PGDB_A046193

Assay: % DegradationTarget: CDK2QC: standardized
Activity overview

IC50 = 0.067 uM

TargetCDK2
Cell lineHEK293
Time6 h
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS002528
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007948
Compound IDPGDB_C007948
Compound17;17;17
Source record IDPGDB_C007948
InChIKeyTZJMCJWHPQQGNJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002528
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Treatment time6 h
TargetCDK2
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

17;17;17

17;17;17 enlarged structure17;17;17 location on patent page 21
Activity table
Page 525 · table start
Page 526 · table end