Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C007948
7 activity records1 related patents
2D structure
CC1(C)CCc2nc(COC(=O)NCc3ccc4c(c3)C(=O)N(C3CCC(=O)NC3=O)C4)sc2C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 49 | % | 10 uM | 18 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A013106 | PGDB_C007948 | PGDB_AS001468 | View |
| IC50 | - | = | 0.066 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A030890 | PGDB_C007948 | PGDB_AS002309 | View |
| IC50 | - | = | 31 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A043058 | PGDB_C007948 | PGDB_AS002070 | View |
| IC50 | - | = | 0.067 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A046193 | PGDB_C007948 | PGDB_AS002528 | View |
| Dmax | - | = | 49 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A051216 | PGDB_C007948 | PGDB_AS002435 | View |
| IC50 | - | = | 31 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A058252 | PGDB_C007948 | PGDB_AS002153 | View |
| IC50 | - | = | 0.082 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A066024 | PGDB_C007948 | PGDB_AS001908 | View |