Activity record

PGDB_A049317

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

Dmax = 4.8 %

TargetGSPT1
Cell lineHEK293
Concentration10 uM
Time6 h
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS000429
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008018
Compound IDPGDB_C008018
Compound114;114
Source record IDPGDB_C008018
InChIKeyXPUDGRLZPKICAX-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000429
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Concentration10 uM
Treatment time6 h
TargetGSPT1
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

114;114

114;114 enlarged structure114;114 location on patent page 28
Activity table
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