Activity record

PGDB_A050246

Assay: bindingTarget: CRBNQC: ambiguous
Activity overview

Kd = 9.9 nM

TargetCRBN
E3 ligaseCRBN
Cell lineHEK293
Time1 h
Assay / ReadoutKd / binding
Assay IDPGDB_AS001216
PatentIL323841A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019545
Compound IDPGDB_C019545
CompoundReference Compound 2
Source record IDPGDB_C001365
InChIKeyFURMQZYSFFTQLK-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001216
Assay familybinding
Assay systemcell_based
ReadoutKd
Treatment time1 h
TargetCRBN | DDB1
E3CRBN | DDB1
Cell lineHEK293

Source evidence

Patent IDIL323841A
Compound location

Reference Compound 2

Reference Compound 2 enlarged structureReference Compound 2 location on patent page 57
Activity table
Page 58 · table single