Activity record

PGDB_A050659

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

degradation = 9 %

TargetGSPT1
Concentration100 nM
Assay / Readout% Degradation
Assay IDPGDB_AS002431
PatentWO2024059107A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002835
Compound IDPGDB_C002835
Compound74;74;74
Source record IDPGDB_C002835
InChIKeyHGLQKZHORDECOX-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002431
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Concentration100 nM
Detection targetprotein_degradation
TargetGSPT1
E3Not specified

Source evidence

Patent IDWO2024059107A1
Compound location

74;74;74

74;74;74 enlarged structure74;74;74 location on patent page 10
Activity table
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