Assay

PGDB_AS002431

System: cell_basedTarget: GSPT1
Assay context summary

Assay context

44 activity records
Assay family% Degradation
Systemcell_based
Readout% Degradation
TargetGSPT1
E3Not specified
Detection targetprotein_degradation
Activity compounds and values

Activity records

44 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C002837
% Degradation-=6.1%100 nM-GSPT1--WO2024059107A1PGDB_A008001PGDB_C002837PGDB_AS002431View
2D structure for PGDB_C002826
% Degradation-=12.5%100 nM-GSPT1--WO2024059107A1PGDB_A008406PGDB_C002826PGDB_AS002431View
2D structure for PGDB_C002834
% Degradation-=9.2%100 nM-GSPT1--WO2024059107A1PGDB_A009147PGDB_C002834PGDB_AS002431View
2D structure for PGDB_C002807
% Degradation-=9.9%100 nM-GSPT1--WO2024059107A1PGDB_A010433PGDB_C002807PGDB_AS002431View
2D structure for PGDB_C002842
% Degradation-=9.7%100 nM-GSPT1--WO2024059107A1PGDB_A011897PGDB_C002842PGDB_AS002431View
2D structure for PGDB_C002815
% Degradation-=1.2%100 nM-GSPT1--WO2024059107A1PGDB_A015210PGDB_C002815PGDB_AS002431View
2D structure for PGDB_C002812
% Degradation-=9%100 nM-GSPT1--WO2024059107A1PGDB_A015285PGDB_C002812PGDB_AS002431View
2D structure for PGDB_C002839
% Degradation-=1.6%100 nM-GSPT1--WO2024059107A1PGDB_A015556PGDB_C002839PGDB_AS002431View
2D structure for PGDB_C002808
% Degradation-=25.3%100 nM-GSPT1--WO2024059107A1PGDB_A016801PGDB_C002808PGDB_AS002431View
2D structure for PGDB_C002849
% Degradation-=5.5%100 nM-GSPT1--WO2024059107A1PGDB_A018609PGDB_C002849PGDB_AS002431View
2D structure for PGDB_C002821
% Degradation-=29%100 nM-GSPT1--WO2024059107A1PGDB_A019114PGDB_C002821PGDB_AS002431View
2D structure for PGDB_C002809
% Degradation-=7.6%100 nM-GSPT1--WO2024059107A1PGDB_A026116PGDB_C002809PGDB_AS002431View
2D structure for PGDB_C002845
% Degradation-=9.3%100 nM-GSPT1--WO2024059107A1PGDB_A028048PGDB_C002845PGDB_AS002431View
2D structure for PGDB_C002836
% Degradation-=3.7%100 nM-GSPT1--WO2024059107A1PGDB_A033465PGDB_C002836PGDB_AS002431View
2D structure for PGDB_C002817
% Degradation-=-0.1%100 nM-GSPT1--WO2024059107A1PGDB_A035242PGDB_C002817PGDB_AS002431View
2D structure for PGDB_C002806
% Degradation-=0%100 nM-GSPT1--WO2024059107A1PGDB_A035267PGDB_C002806PGDB_AS002431View
2D structure for PGDB_C002848
% Degradation-=1.6%100 nM-GSPT1--WO2024059107A1PGDB_A036440PGDB_C002848PGDB_AS002431View
2D structure for PGDB_C002830
% Degradation-=11.1%100 nM-GSPT1--WO2024059107A1PGDB_A039125PGDB_C002830PGDB_AS002431View
2D structure for PGDB_C002828
% Degradation-=0.4%100 nM-GSPT1--WO2024059107A1PGDB_A039376PGDB_C002828PGDB_AS002431View
2D structure for PGDB_C002825
% Degradation-=11.7%100 nM-GSPT1--WO2024059107A1PGDB_A041751PGDB_C002825PGDB_AS002431View
Page 1 of 3 · 44 records