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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A052538

Assay: % DegradationTarget: CSNK1A1QC: standardized

Activity overview

DC50 = 0.218 uM

TargetCSNK1A1

E3 ligaseCRBN

Cell lineHT-1080

Time20 h

Assay / Readoutluminescence / DC50

Assay IDPGDB_AS001868

PatentWO2022257897A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C001835

Compound38

Source record IDPGDB_C001835

InChIKeyYVIFTSASGXHSFZ-JFGZAKSSSA-N

Assay context

Assay IDPGDB_AS001868

Assay family% Degradation

Assay systemcell_based

ReadoutDC50

Technologyluminescence

Treatment time20 h

Detection targetprotein_degradation

TargetCSNK1A1

E3CRBN

Cell lineHT-1080

OrganismHomo sapiens

Source evidence

Patent IDWO2022257897A1

Compound location

38

38 enlarged structure

38 location on patent page 103

Activity table

Page 134 · table start

Page 135 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU