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O=C1CCC(N2Cc3cc(C(=O)N[C@H](c4ccc(F)cc4)C4CCOCC4)ccc3C2=O)C(=O)N1| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 64.1 | % | 10 uM | 20 h | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A009193 | PGDB_C001835 | PGDB_AS000920 | View | |
| Dmax | - | = | 19.9 | % | 10 uM | 20 h | GSPT1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A041792 | PGDB_C001835 | PGDB_AS000618 | View | |
| DC50 | - | = | 0.218 | uM | - | — | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A052538 | PGDB_C001835 | PGDB_AS001868 | View |