Activity record

PGDB_A055171

Assay: bindingTarget: CRBNQC: standardized
Activity overview

Ki = 1.49 uM

TargetCRBN
E3 ligaseCRBN
Time60 min
Assay / Readoutfluorescence / Ki
Assay IDPGDB_AS002388
PatentUS12110292B2
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019024
Compound IDPGDB_C019024
CompoundLenalidomide;Lenalidomide;Lenalidomide;Lenalidomide
Source record IDPGDB_C000057
InChIKeyGOTYRUGSSMKFNF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002388
Assay familybinding
Assay systembiochemical
ReadoutKi
Technologyfluorescence
Treatment time60 min
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDUS12110292B2
Compound location

Lenalidomide;Lenalidomide;Lenalidomide;Lenalidomide

Lenalidomide;Lenalidomide;Lenalidomide;Lenalidomide enlarged structureLenalidomide;Lenalidomide;Lenalidomide;Lenalidomide location on patent page 54
Activity table
Page 102 · table start
Page 103 · table end