Activity record

PGDB_A056459

Assay: % DegradationTarget: CDK2QC: standardized
Activity overview

Dmax = 20 %

TargetCDK2
Cell lineHEK293
Concentration10 uM
Time6 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS002435
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007933
Compound IDPGDB_C007933
Compound2;2;2
Source record IDPGDB_C007933
InChIKeyIDMQAYPBFWKNRB-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002435
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Concentration10 uM
Treatment time6 h
TargetCDK2
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

2;2;2

2;2;2 enlarged structure2;2;2 location on patent page 21
Activity table
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