Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C007933
5 activity records1 related patents
2D structure
O=C1CCC(N2Cc3ccc(CNC(=O)OCc4nc5ccccc5s4)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 28 | % | 10 uM | 18 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A015684 | PGDB_C007933 | PGDB_AS001468 | View |
| IC50 | - | = | 0.11 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A033143 | PGDB_C007933 | PGDB_AS002309 | View |
| IC50 | - | = | 0.041 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A042490 | PGDB_C007933 | PGDB_AS001908 | View |
| Dmax | - | = | 20 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A056459 | PGDB_C007933 | PGDB_AS002435 | View |
| IC50 | - | = | 0.098 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A067482 | PGDB_C007933 | PGDB_AS002528 | View |