Activity record

PGDB_A058369

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

IC50 = 10 uM

TargetGSPT1
Cell lineHEK293
Time6 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002153
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007968
Compound IDPGDB_C007968
Compound37;37;37;37
Source record IDPGDB_C007968
InChIKeyCRXBCGRSDCOWIQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002153
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time6 h
TargetGSPT1
E3Not specified
Cell lineHEK293
OrganismHomo sapiens

Source evidence

Patent IDWO2025043225
Compound location

37;37;37;37

37;37;37;37 enlarged structure37;37;37;37 location on patent page 23
Activity table
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