Activity record

PGDB_A058626

Assay: viabilityTarget: IKZF3QC: standardized
Activity overview

inhibition = 40-50 %

TargetIKZF3
Cell lineTMD8
Concentration500 nM
Time96 h
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS002558
PatentWO2025162225A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024192
Compound IDPGDB_C024192
CompoundGT-06441
Source record IDPGDB_C024192
InChIKeySGMTWHICBZBTSZ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002558
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration500 nM
Treatment time96 h
Detection target% Cell viability
TargetIKZF3
E3Not specified
Cell lineTMD8
OrganismHomo sapiens

Source evidence

Patent IDWO2025162225A1
Compound location

GT-06441

GT-06441 enlarged structureGT-06441 location on patent page 22
Activity table
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