Activity record

PGDB_A058893

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

degradation = 50-80 %

TargetGSPT1
Concentration0.1 uM
Assay / Readoutpercent_remaining / % Degradation
Assay IDPGDB_AS001685
PatentUS20200369679A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C004436
Compound IDPGDB_C004436
CompoundII-1;II-1
Source record IDPGDB_C004436
InChIKeyHJUJZDGYQLBHSD-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001685
Assay family% Degradation
Assay systemcell_based
Readoutpercent_remaining
Concentration0.1 uM
Detection targetprotein_degradation
TargetGSPT1
E3Not specified

Source evidence

Patent IDUS20200369679A1
Compound location

II-1;II-1

II-1;II-1 enlarged structureII-1;II-1 location on patent page 158
Activity table
Page 185 · table single