Activity record

PGDB_A062143

Assay: viabilityTarget: GSPT1QC: ambiguous
Activity overview

GI50 = 5.62 nM

TargetGSPT1
Cell lineHep3B
Time48 h
Assay / ReadoutGI50 / viability
Assay IDPGDB_AS001914
PatentWO2023237116A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002218
Compound IDPGDB_C002218
CompoundExample 81
Source record IDPGDB_C002218
InChIKeySXPFVDFMNAKNII-NUJJYFHVSA-N

Assay context

Assay IDPGDB_AS001914
Assay familyviability
Assay systemcell_based
ReadoutGI50
Treatment time48 h
Detection target% Cell viability
TargetGSPT1
E3Not specified
Cell lineHep3B

Source evidence

Patent IDWO2023237116A1
Compound location

Example 81

Example 81 enlarged structureExample 81 location on patent page 261
Activity table
Page 382 · table single