Activity record

PGDB_A062273

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

inhibition = 53-60 %

TargetCRBN
E3 ligaseCRBN
Concentration2 uM
Assay / ReadoutHTRF / % Inhibition
Assay IDPGDB_AS001462
PatentCN120548310A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000922
Compound IDPGDB_C000922
CompoundGT-09851
Source record IDPGDB_C000922
InChIKeyGCHHSGLHHCAOPB-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001462
Assay familybiochemical
Assay systemcell_based
Readout% Inhibition
TechnologyHTRF
Concentration2 uM
Detection targetcell_inhibition
TargetCRBN
E3CRBN

Source evidence

Patent IDCN120548310A
Compound location

GT-09851

GT-09851 enlarged structureGT-09851 location on patent page 41
Activity table
Page 147 · table start
Page 148 · table end