Activity record

PGDB_A062624

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 241.42 nM

TargetCRBN
E3 ligaseCRBN
Time15 min
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000570
PatentCN118852145A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001474
Compound IDPGDB_C001474
Compound实施例26
Source record IDPGDB_C001474
InChIKeyWGAQSDUJGWAXDH-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000570
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time15 min
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDCN118852145A
Compound location

实施例26

实施例26 enlarged structure实施例26 location on patent page 62
Activity table
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