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Compound
PGDB_C001474
4 activity records1 related patents
2D structure
CC(C)(c1ccc(NC(=O)OCc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)cc1)c1ccc(OC(F)F)cc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 92.09 | % | Concentration series: 1 uM | 24 h | GSPT1 | - | HEK293 | CN118852145A | PGDB_A027256 | PGDB_C001474 | PGDB_AS002339 | View |
| DC50 | - | = | 5.64 | nM | - | — | GSPT1 | - | HEK293 | CN118852145A | PGDB_A059678 | PGDB_C001474 | PGDB_AS001853 | View |
| IC50 | - | = | 241.42 | nM | - | — | CRBN | CRBN | - | CN118852145A | PGDB_A062624 | PGDB_C001474 | PGDB_AS000570 | View |
| IC50 | - | = | 20.2 | nM | - | — | GSPT1 | - | NCI-H1155 | CN118852145A | PGDB_A070649 | PGDB_C001474 | PGDB_AS001039 | View |