Activity record

PGDB_A064180

Assay: viabilityTarget: GSPT1QC: ambiguous
Activity overview

GI50 = 6.91 nM

TargetGSPT1
Cell lineNCI-H929
Time48 h
Assay / Readoutluminescence / GI50
Assay IDPGDB_AS000710
PatentWO2023237116A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002208
Compound IDPGDB_C002208
CompoundExample 10;Example 10
Source record IDPGDB_C002208
InChIKeyVDWYJLXTCZENAQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000710
Assay familyviability
Assay systemcell_based
ReadoutGI50
Technologyluminescence
Treatment time48 h
Detection target% Cell viability
TargetGSPT1
E3Not specified
Cell lineNCI-H929

Source evidence

Patent IDWO2023237116A1
Compound location

Example 10;Example 10

Example 10;Example 10 enlarged structureExample 10;Example 10 location on patent page 138
Activity table
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