Activity record

PGDB_A074411

Assay: % DegradationQC: standardized
Activity overview

DC50 = 0.16 nM

Cell lineNCI-H929
Time24 h
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS000575
PatentEP4685141A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C025625
Compound IDPGDB_C025625
Compound实施例 31
Source record IDPGDB_C025625
InChIKeyFKTSELREKVXTEN-MUUNZHRXSA-N

Assay context

Assay IDPGDB_AS000575
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time24 h
E3Not specified
Cell lineNCI-H929
OrganismHomo sapiens

Source evidence

Patent IDEP4685141A1
Compound location

实施例 31

实施例 31 enlarged structure实施例 31 location on patent page 52
Activity table
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