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Compound
PGDB_C025625
5 activity records1 related patents
2D structure
O=C1CC[C@@H](N2C(=O)c3cccc4c(Cc5ccc(CN6CCN(c7cc(-n8cnc(C(F)(F)F)c8)ncn7)CC6)cc5)ccc2c34)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 75 | % | Concentration series: 1600 nM, 400 nM, 100 nM, 25 nM, 6.25 nM, 1.56 nM, 0.39 nM, 0.1 nM | 24 h | - | - | NCI-H929 | EP4685141A1 | PGDB_A024951 | PGDB_C025625 | PGDB_AS002256 | View |
| DC50 | - | = | 0.34 | nM | - | — | - | - | NCI-H929 | EP4685141A1 | PGDB_A044626 | PGDB_C025625 | PGDB_AS001024 | View |
| Dmax | - | = | 77 | % | Concentration series: 1600 nM, 400 nM, 100 nM, 25 nM, 6.25 nM, 1.56 nM, 0.39 nM, 0.1 nM | 24 h | - | - | NCI-H929 | EP4685141A1 | PGDB_A063874 | PGDB_C025625 | PGDB_AS000327 | View |
| IC50 | - | = | 0.01 | nM | - | — | - | - | NCI-H929 | EP4685141A1 | PGDB_A071769 | PGDB_C025625 | PGDB_AS001501 | View |
| DC50 | - | = | 0.16 | nM | - | — | - | - | NCI-H929 | EP4685141A1 | PGDB_A074411 | PGDB_C025625 | PGDB_AS000575 | View |