Activity record

PGDB_A076050

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 = 0.71 uM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutIC50 / binding
Assay IDPGDB_AS000958
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008034
Compound IDPGDB_C008034
Compound53;53;53
Source record IDPGDB_C008034
InChIKeyOOFCGNUCBGMBGK-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000958
Assay familybinding
Assay systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025043225
Compound location

53;53;53

53;53;53 enlarged structure53;53;53 location on patent page 40
Activity table
Page 528 · table start
Page 529 · table end