Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C008034
7 activity records1 related patents
2D structure
O=C1CCC(N2Cc3ccc(CNC(=O)OC4CN(Cc5ccccc5)C4)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 0.12 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A027147 | PGDB_C008034 | PGDB_AS000366 | View |
| IC50 | - | = | 31 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A037828 | PGDB_C008034 | PGDB_AS001575 | View |
| Dmax | - | = | 29 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A040700 | PGDB_C008034 | PGDB_AS000735 | View |
| IC50 | - | = | 0.31 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A041189 | PGDB_C008034 | PGDB_AS002405 | View |
| IC50 | - | = | 31 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A041920 | PGDB_C008034 | PGDB_AS002508 | View |
| Dmax | - | = | 22 | % | 10 uM | 18 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A046930 | PGDB_C008034 | PGDB_AS002240 | View |
| IC50 | - | = | 0.71 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A076050 | PGDB_C008034 | PGDB_AS000958 | View |