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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A076514

Assay: viabilityTarget: IKZF3QC: standardized

Activity overview

inhibition = 40-50 %

TargetIKZF3

Cell lineH196

Concentration500 nM

Time96 h

Assay / Readout% Inhibition / viability

Assay IDPGDB_AS000866

PatentWO2025162225A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C024359

CompoundGT-10146

Source record IDPGDB_C024359

InChIKeyJCZJODDMGGWEOA-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000866

Assay familyviability

Assay systemcell_based

Readout% Inhibition

Concentration500 nM

Treatment time96 h

Detection target% Cell viability

TargetIKZF3

E3Not specified

Cell lineH196

OrganismHomo sapiens

Source evidence

Patent IDWO2025162225A1

Compound location

GT-10146

GT-10146 enlarged structure

GT-10146 location on patent page 25

Activity table

Page 155 · table start

Page 156 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU