Activity record

PGDB_A077553

Assay: % DegradationTarget: BRD4QC: ambiguous
Activity overview

degradation = 30-60 %

TargetBRD4
Concentration1 uM
Assay / ReadoutWestern_blot / % Degradation
Assay IDPGDB_AS002272
PatentCN117683022A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000356
Compound IDPGDB_C000356
Compound18;18
Source record IDPGDB_C000356
InChIKeyAFYKDDQRWHNAPE-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002272
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
TechnologyWestern_blot
Concentration1 uM
Detection targetprotein_degradation
TargetBRD4
E3Not specified

Source evidence

Patent IDCN117683022A
Compound location

18;18

18;18 enlarged structure18;18 location on patent page 3
Activity table
Page 17 · table single