Activity record

PGDB_A077636

Assay: viabilityTarget: GSPT1QC: ambiguous
Activity overview

GI50 = 0.5 nM

TargetGSPT1
Cell lineSU-DHL-2
Time48 h
Assay / ReadoutGI50 / viability
Assay IDPGDB_AS000205
PatentWO2023237116A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002262
Compound IDPGDB_C002262
CompoundExample 89
Source record IDPGDB_C002262
InChIKeyIHLKWEILLYYUJX-YOQWSDCESA-N

Assay context

Assay IDPGDB_AS000205
Assay familyviability
Assay systemcell_based
ReadoutGI50
Treatment time48 h
Detection target% Cell viability
TargetGSPT1
E3Not specified
Cell lineSU-DHL-2

Source evidence

Patent IDWO2023237116A1
Compound location

Example 89

Example 89 enlarged structureExample 89 location on patent page 282
Activity table
Page 381 · table single