Activity record

PGDB_A081456

Assay: % DegradationTarget: VAV1QC: standardized
Activity overview

DC50 <= 50 nM

TargetVAV1
Cell lineJurkat
Assay / Readoutfluorescence / DC50
Assay IDPGDB_AS001390
PatentWO2026061428A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010388
Compound IDPGDB_C010388
Compound189
Source record IDPGDB_C030255
InChIKeyXFTKTXZPWJMLPJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001390
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyfluorescence
TargetVAV1
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDWO2026061428A1
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