Assay

PGDB_AS000014

System: cell_basedTarget: BRAFCell line: A375.10
Assay context summary

Assay context

52 activity records
Assay family% Degradation
Systemcell_based
ReadoutEmax
TargetBRAF
E3Not specified
Cell lineA375.10
Technologyluminescence
Activity compounds and values

Activity records

52 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C005704
Emax-=10.89%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A010527PGDB_C005704PGDB_AS000014View
2D structure for PGDB_C005701
Emax-=15.62%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A011581PGDB_C005701PGDB_AS000014View
2D structure for PGDB_C005693
Emax-=7.08%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A013491PGDB_C005693PGDB_AS000014View
2D structure for PGDB_C005703
Emax-=13.37%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A014556PGDB_C005703PGDB_AS000014View
2D structure for PGDB_C005728
Emax-=8.31%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A018725PGDB_C005728PGDB_AS000014View
2D structure for PGDB_C005709
Emax-=11.64%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A019719PGDB_C005709PGDB_AS000014View
2D structure for PGDB_C005716
Emax-=9.52%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A019789PGDB_C005716PGDB_AS000014View
2D structure for PGDB_C005707
Emax-=12.05%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A020437PGDB_C005707PGDB_AS000014View
2D structure for PGDB_C005698
Emax-=11.33%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A021550PGDB_C005698PGDB_AS000014View
2D structure for PGDB_C005729
Emax-=13.19%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A022002PGDB_C005729PGDB_AS000014View
2D structure for PGDB_C005726
Emax-=12.02%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A022739PGDB_C005726PGDB_AS000014View
2D structure for PGDB_C005718
Emax-=15.38%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A023998PGDB_C005718PGDB_AS000014View
2D structure for PGDB_C005692
Emax-=15.74%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A027395PGDB_C005692PGDB_AS000014View
2D structure for PGDB_C005724
Emax-=10.53%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A027870PGDB_C005724PGDB_AS000014View
2D structure for PGDB_C005720
Emax-=8.05%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A028183PGDB_C005720PGDB_AS000014View
2D structure for PGDB_C005732
Emax-=12.88%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A029064PGDB_C005732PGDB_AS000014View
2D structure for PGDB_C005695
Emax-=8.88%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A029068PGDB_C005695PGDB_AS000014View
2D structure for PGDB_C005694
Emax-=9.27%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A032780PGDB_C005694PGDB_AS000014View
2D structure for PGDB_C005708
Emax-=14.67%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A032787PGDB_C005708PGDB_AS000014View
2D structure for PGDB_C005722
Emax-=9.52%10 uM24 hBRAF-A375.10AU2022290851A1PGDB_A037792PGDB_C005722PGDB_AS000014View
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