PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

81 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

TargetIKZF2

E3Not specified

Cell lineHEK293T

Technologyfluorescence

Activity compounds and values

Activity records

81 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	<	15	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A009006	PGDB_C000451	PGDB_AS000278	View
% Degradation	-	=	32.7	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A009659	PGDB_C000408	PGDB_AS000278	View
% Degradation	-	=	84.9	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A010311	PGDB_C000409	PGDB_AS000278	View
% Degradation	-	=	92.3	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A011322	PGDB_C000469	PGDB_AS000278	View
% Degradation	-	=	85.8	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A011336	PGDB_C000407	PGDB_AS000278	View
% Degradation	-	=	37.8	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A011615	PGDB_C000415	PGDB_AS000278	View
% Degradation	-	=	74.2	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A012541	PGDB_C000401	PGDB_AS000278	View
% Degradation	-	=	42.5	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A013890	PGDB_C000416	PGDB_AS000278	View
% Degradation	-	=	74.4	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A013984	PGDB_C000401	PGDB_AS000278	View
% Degradation	-	<	15	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A014022	PGDB_C000395	PGDB_AS000278	View
% Degradation	-	<	15	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A015388	PGDB_C000405	PGDB_AS000278	View
% Degradation	-	=	80.2	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A015451	PGDB_C000393	PGDB_AS000278	View
% Degradation	-	<	15	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A017209	PGDB_C000394	PGDB_AS000278	View
% Degradation	-	=	38.1	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A017642	PGDB_C000404	PGDB_AS000278	View
% Degradation	-	<	15	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A017725	PGDB_C000419	PGDB_AS000278	View
% Degradation	-	=	83.2	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A017842	PGDB_C000464	PGDB_AS000278	View
% Degradation	-	=	77.2	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A018176	PGDB_C000470	PGDB_AS000278	View
% Degradation	-	=	75.9	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A019013	PGDB_C000462	PGDB_AS000278	View
% Degradation	-	<	15	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A019516	PGDB_C000417	PGDB_AS000278	View
% Degradation	-	<	15	%	1 uM	24 h	IKZF2	-	HEK293T	US20230265071A1	PGDB_A019565	PGDB_C000431	PGDB_AS000278	View

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