PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

76 activity records

Assay familyviability

Systemcell_based

ReadoutIC50

E3Not specified

Cell lineMDA-MB-231

Detection targetcell_proliferation

Activity compounds and values

Activity records

76 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
IC50	-	=	0.85	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A008020	PGDB_C007314	PGDB_AS000401	View
IC50	-	=	209.9	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A009306	PGDB_C007293	PGDB_AS000401	View
IC50	-	=	385.8	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A009397	PGDB_C007310	PGDB_AS000401	View
IC50	-	=	236.6	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A010021	PGDB_C007252	PGDB_AS000401	View
IC50	-	=	0.37	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A010256	PGDB_C007253	PGDB_AS000401	View
IC50	-	=	34.5	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A011449	PGDB_C007263	PGDB_AS000401	View
IC50	-	=	637.02	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A011935	PGDB_C007271	PGDB_AS000401	View
IC50	-	=	124	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A016375	PGDB_C007307	PGDB_AS000401	View
IC50	-	=	5.7	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A016531	PGDB_C007281	PGDB_AS000401	View
IC50	-	=	25	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A017199	PGDB_C007294	PGDB_AS000401	View
IC50	-	=	314.7	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A018146	PGDB_C007301	PGDB_AS000401	View
IC50	-	=	14.12	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A018166	PGDB_C007245	PGDB_AS000401	View
IC50	-	=	27.1	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A018221	PGDB_C007284	PGDB_AS000401	View
IC50	-	=	158.7	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A019521	PGDB_C007303	PGDB_AS000401	View
IC50	-	=	7.98	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A021374	PGDB_C007315	PGDB_AS000401	View
IC50	-	=	195.8	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A021508	PGDB_C007305	PGDB_AS000401	View
IC50	-	=	983.9	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A022088	PGDB_C007292	PGDB_AS000401	View
IC50	-	=	97	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A022470	PGDB_C007270	PGDB_AS000401	View
IC50	-	=	819.7	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A022979	PGDB_C007290	PGDB_AS000401	View
IC50	-	=	213.3	nM	-	—	CDK12	-	MDA-MB-231	CN120590389A	PGDB_A024133	PGDB_C007264	PGDB_AS000401	View

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