PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberCN120590389A

AssigneeFujian Normal University, Shanghai Institute Of Materia Medica Of Cas

TitlePurine compounds and their preparation methods and uses

Family ID96896283

Family members1

Filing year2024

Publication date2025-09-05

JurisdictionCN

Compounds76

Activity records101

Assays2

Activity compounds and values

Activity records

101 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
IC50	-	=	0.85	nM	-	—	CDK12	-	MDA-MB-231	PGDB_A008020	PGDB_C007314	PGDB_AS000401	View
IC50	-	=	209.9	nM	-	—	CDK12	-	MDA-MB-231	PGDB_A009306	PGDB_C007293	PGDB_AS000401	View
IC50	-	=	385.8	nM	-	—	CDK12	-	MDA-MB-231	PGDB_A009397	PGDB_C007310	PGDB_AS000401	View
IC50	-	=	21.45	nM	-	—	CDK12	-	MDA-MB-468	PGDB_A009502	PGDB_C007266	PGDB_AS000658	View
IC50	-	=	236.6	nM	-	—	CDK12	-	MDA-MB-231	PGDB_A010021	PGDB_C007252	PGDB_AS000401	View
IC50	-	=	0.37	nM	-	—	CDK12	-	MDA-MB-231	PGDB_A010256	PGDB_C007253	PGDB_AS000401	View
IC50	-	=	0.03	nM	-	—	CDK12	-	MDA-MB-468	PGDB_A010315	PGDB_C007253	PGDB_AS000658	View
IC50	-	=	3.103	nM	-	—	CDK12	-	MDA-MB-468	PGDB_A010568	PGDB_C007246	PGDB_AS000658	View
IC50	-	=	34.5	nM	-	—	CDK12	-	MDA-MB-231	PGDB_A011449	PGDB_C007263	PGDB_AS000401	View
IC50	-	=	637.02	nM	-	—	CDK12	-	MDA-MB-231	PGDB_A011935	PGDB_C007271	PGDB_AS000401	View
IC50	-	=	18.7	nM	-	—	CDK12	-	MDA-MB-468	PGDB_A012874	PGDB_C007258	PGDB_AS000658	View
IC50	-	=	27.28	nM	-	—	CDK12	-	MDA-MB-468	PGDB_A016153	PGDB_C007256	PGDB_AS000658	View
IC50	-	=	124	nM	-	—	CDK12	-	MDA-MB-231	PGDB_A016375	PGDB_C007307	PGDB_AS000401	View
IC50	-	=	5.7	nM	-	—	CDK12	-	MDA-MB-231	PGDB_A016531	PGDB_C007281	PGDB_AS000401	View
IC50	-	=	25	nM	-	—	CDK12	-	MDA-MB-231	PGDB_A017199	PGDB_C007294	PGDB_AS000401	View
IC50	-	=	314.7	nM	-	—	CDK12	-	MDA-MB-231	PGDB_A018146	PGDB_C007301	PGDB_AS000401	View
IC50	-	=	14.12	nM	-	—	CDK12	-	MDA-MB-231	PGDB_A018166	PGDB_C007245	PGDB_AS000401	View
IC50	-	=	27.1	nM	-	—	CDK12	-	MDA-MB-231	PGDB_A018221	PGDB_C007284	PGDB_AS000401	View
IC50	-	=	158.7	nM	-	—	CDK12	-	MDA-MB-231	PGDB_A019521	PGDB_C007303	PGDB_AS000401	View
IC50	-	=	7.98	nM	-	—	CDK12	-	MDA-MB-231	PGDB_A021374	PGDB_C007315	PGDB_AS000401	View

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