PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

412 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

TargetSMARCA4

E3Not specified

Cell lineHeLa

OrganismHomo sapiens

Technologyluminescence

Activity compounds and values

Activity records

412 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A007069	PGDB_C027032	PGDB_AS000849	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A007103	PGDB_C027234	PGDB_AS000849	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A007120	PGDB_C026916	PGDB_AS000849	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A007201	PGDB_C027300	PGDB_AS000849	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A007694	PGDB_C027037	PGDB_AS000849	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A008191	PGDB_C027192	PGDB_AS000849	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A008305	PGDB_C027232	PGDB_AS000849	View
% Degradation	-	<	30	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A008378	PGDB_C026891	PGDB_AS000849	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A008628	PGDB_C026967	PGDB_AS000849	View
% Degradation	-	<	30	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A009198	PGDB_C027049	PGDB_AS000849	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A009516	PGDB_C027021	PGDB_AS000849	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A009554	PGDB_C027030	PGDB_AS000849	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A009705	PGDB_C027275	PGDB_AS000849	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A009754	PGDB_C027277	PGDB_AS000849	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A009774	PGDB_C026930	PGDB_AS000849	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A009853	PGDB_C027073	PGDB_AS000849	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A009944	PGDB_C027297	PGDB_AS000849	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A010086	PGDB_C026964	PGDB_AS000849	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A010913	PGDB_C026928	PGDB_AS000849	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA4	-	HeLa	WO2023244806A1	PGDB_A010988	PGDB_C027097	PGDB_AS000849	View

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