Assay

PGDB_AS000910

System: cell_basedTarget: IKZF3Cell line: Jurkat
Assay context summary

Assay context

333 activity records
Assay family% Degradation
Systemcell_based
ReadoutDC50
TargetIKZF3
E3Not specified
Cell lineJurkat
OrganismHomo sapiens
Technologyflow_cytometry
Detection targetprotein_degradation
Activity compounds and values

Activity records

333 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C030801
DC50->10000nM-—IKZF3-JurkatWO2026080794A1PGDB_A000074PGDB_C030801PGDB_AS000910View
2D structure for PGDB_C030815
DC50->10000nM-—IKZF3-JurkatWO2026080794A1PGDB_A000109PGDB_C030815PGDB_AS000910View
2D structure for PGDB_C031034
DC50->10000nM-—IKZF3-JurkatWO2026080794A1PGDB_A000148PGDB_C031034PGDB_AS000910View
2D structure for PGDB_C030906
DC50->10000nM-—IKZF3-JurkatWO2026080794A1PGDB_A000169PGDB_C030906PGDB_AS000910View
2D structure for PGDB_C030851
DC50->10000nM-—IKZF3-JurkatWO2026080794A1PGDB_A000170PGDB_C030851PGDB_AS000910View
2D structure for PGDB_C030830
DC50-=7312nM-—IKZF3-JurkatWO2026080794A1PGDB_A000188PGDB_C030830PGDB_AS000910View
2D structure for PGDB_C030973
DC50->10000nM-—IKZF3-JurkatWO2026080794A1PGDB_A000199PGDB_C030973PGDB_AS000910View
2D structure for PGDB_C030845
DC50->10000nM-—IKZF3-JurkatWO2026080794A1PGDB_A000203PGDB_C030845PGDB_AS000910View
2D structure for PGDB_C031113
DC50-=5377nM-—IKZF3-JurkatWO2026080794A1PGDB_A000206PGDB_C031113PGDB_AS000910View
2D structure for PGDB_C030996
DC50->10000nM-—IKZF3-JurkatWO2026080794A1PGDB_A000305PGDB_C030996PGDB_AS000910View
2D structure for PGDB_C031065
DC50->10000nM-—IKZF3-JurkatWO2026080794A1PGDB_A000318PGDB_C031065PGDB_AS000910View
2D structure for PGDB_C030827
DC50->10000nM-—IKZF3-JurkatWO2026080794A1PGDB_A000323PGDB_C030827PGDB_AS000910View
2D structure for PGDB_C031068
DC50-=579nM-—IKZF3-JurkatWO2026080794A1PGDB_A000362PGDB_C031068PGDB_AS000910View
2D structure for PGDB_C031037
DC50->10000nM-—IKZF3-JurkatWO2026080794A1PGDB_A000401PGDB_C031037PGDB_AS000910View
2D structure for PGDB_C030843
DC50-=8355nM-—IKZF3-JurkatWO2026080794A1PGDB_A000411PGDB_C030843PGDB_AS000910View
2D structure for PGDB_C030999
DC50-=247nM-—IKZF3-JurkatWO2026080794A1PGDB_A000442PGDB_C030999PGDB_AS000910View
2D structure for PGDB_C031083
DC50->10000nM-—IKZF3-JurkatWO2026080794A1PGDB_A000445PGDB_C031083PGDB_AS000910View
2D structure for PGDB_C030946
DC50-=456nM-—IKZF3-JurkatWO2026080794A1PGDB_A000500PGDB_C030946PGDB_AS000910View
2D structure for PGDB_C031021
DC50-=4102nM-—IKZF3-JurkatWO2026080794A1PGDB_A000514PGDB_C031021PGDB_AS000910View
2D structure for PGDB_C030974
DC50->10000nM-—IKZF3-JurkatWO2026080794A1PGDB_A000567PGDB_C030974PGDB_AS000910View
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