PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberWO2026080794A1

AssigneeBristol Myers Squibb

TitleChemical compounds useful for degrading proteins

Family IDunresolved_family_WO2026080794A1

Family members1

Filing year2025

Publication date2026-04-16

JurisdictionWO

Compounds339

Activity records2,034

Assays6

Activity compounds and values

Activity records

2,022 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
DC50	-	=	52	nM	-	—	IKZF2	-	Jurkat	PGDB_A000007	PGDB_C030846	PGDB_AS001885	View
Dmax	-	=	92	%	-	24 h	IKZF2	-	Jurkat	PGDB_A000018	PGDB_C030788	PGDB_AS000354	View
DC50	-	=	92	nM	-	—	IKZF1	-	Jurkat	PGDB_A000023	PGDB_C030999	PGDB_AS000302	View
Dmax	-	=	50	%	-	24 h	IKZF3	-	Jurkat	PGDB_A000027	PGDB_C030781	PGDB_AS000982	View
Dmax	-	=	61	%	-	24 h	IKZF1	-	Jurkat	PGDB_A000034	PGDB_C031048	PGDB_AS000804	View
DC50	-	=	10	nM	-	—	IKZF2	-	Jurkat	PGDB_A000038	PGDB_C030910	PGDB_AS001885	View
DC50	-	=	1810	nM	-	—	IKZF1	-	Jurkat	PGDB_A000054	PGDB_C030912	PGDB_AS000302	View
DC50	-	=	8	nM	-	—	IKZF2	-	Jurkat	PGDB_A000056	PGDB_C031127	PGDB_AS001885	View
DC50	-	=	506	nM	-	—	IKZF1	-	Jurkat	PGDB_A000065	PGDB_C030904	PGDB_AS000302	View
Dmax	-	=	92	%	-	24 h	IKZF2	-	Jurkat	PGDB_A000066	PGDB_C030883	PGDB_AS000354	View
Dmax	-	=	56	%	-	24 h	IKZF1	-	Jurkat	PGDB_A000071	PGDB_C030872	PGDB_AS000804	View
DC50	-	>	10000	nM	-	—	IKZF3	-	Jurkat	PGDB_A000074	PGDB_C030801	PGDB_AS000910	View
DC50	-	=	26	nM	-	—	IKZF2	-	Jurkat	PGDB_A000085	PGDB_C031001	PGDB_AS001885	View
DC50	-	=	29	nM	-	—	IKZF2	-	Jurkat	PGDB_A000091	PGDB_C030974	PGDB_AS001885	View
Dmax	-	=	15	%	-	24 h	IKZF1	-	Jurkat	PGDB_A000093	PGDB_C030798	PGDB_AS000804	View
DC50	-	=	231	nM	-	—	IKZF2	-	Jurkat	PGDB_A000094	PGDB_C030862	PGDB_AS001885	View
DC50	-	=	2	nM	-	—	IKZF2	-	Jurkat	PGDB_A000103	PGDB_C030952	PGDB_AS001885	View
Dmax	-	=	63	%	-	24 h	IKZF3	-	Jurkat	PGDB_A000106	PGDB_C030776	PGDB_AS000982	View
DC50	-	>	10000	nM	-	—	IKZF3	-	Jurkat	PGDB_A000109	PGDB_C030815	PGDB_AS000910	View
DC50	-	=	6	nM	-	—	IKZF2	-	Jurkat	PGDB_A000112	PGDB_C030981	PGDB_AS001885	View

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