Assay

PGDB_AS000990

System: cell_basedTarget: KRASCell line: H358
Assay context summary

Assay context

58 activity records
Assay familyviability
Systemcell_based
ReadoutIC50
TargetKRAS
E3Not specified
Cell lineH358
OrganismHomo sapiens
Detection target% Cell viability
Activity compounds and values

Activity records

58 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C031956
IC50-=11.7nM-—KRASCRBNH358WO2026114958A1PGDB_A000116PGDB_C031956PGDB_AS000990View
2D structure for PGDB_C031964
IC50-=14.4nM-—KRASCRBNH358WO2026114958A1PGDB_A000124PGDB_C031964PGDB_AS000990View
2D structure for PGDB_C031967
IC50-=3.7nM-—KRASCRBNH358WO2026114958A1PGDB_A000165PGDB_C031967PGDB_AS000990View
2D structure for PGDB_C031982
IC50-=5.9nM-—KRASCRBNH358WO2026114958A1PGDB_A000195PGDB_C031982PGDB_AS000990View
2D structure for PGDB_C031942
IC50-=1.3nM-—KRASCRBNH358WO2026114958A1PGDB_A000601PGDB_C031942PGDB_AS000990View
2D structure for PGDB_C031985
IC50-=2.4nM-—KRASCRBNH358WO2026114958A1PGDB_A001135PGDB_C031985PGDB_AS000990View
2D structure for PGDB_C031943
IC50-=3.9nM-—KRASCRBNH358WO2026114958A1PGDB_A001291PGDB_C031943PGDB_AS000990View
2D structure for PGDB_C031992
IC50-=3.2nM-—KRASCRBNH358WO2026114958A1PGDB_A001295PGDB_C031992PGDB_AS000990View
2D structure for PGDB_C031954
IC50-=8.2nM-—KRASCRBNH358WO2026114958A1PGDB_A001330PGDB_C031954PGDB_AS000990View
2D structure for PGDB_C031990
IC50-=3.8nM-—KRASCRBNH358WO2026114958A1PGDB_A001384PGDB_C031990PGDB_AS000990View
2D structure for PGDB_C031976
IC50-=20.5nM-—KRASCRBNH358WO2026114958A1PGDB_A001651PGDB_C031976PGDB_AS000990View
2D structure for PGDB_C031952
IC50-=3.6nM-—KRASCRBNH358WO2026114958A1PGDB_A001847PGDB_C031952PGDB_AS000990View
2D structure for PGDB_C031976
IC50-=4.1nM-—KRASCRBNH358WO2026114958A1PGDB_A001973PGDB_C031976PGDB_AS000990View
2D structure for PGDB_C031977
IC50-=2.9nM-—KRASCRBNH358WO2026114958A1PGDB_A002521PGDB_C031977PGDB_AS000990View
2D structure for PGDB_C031957
IC50-=12.4nM-—KRASCRBNH358WO2026114958A1PGDB_A002605PGDB_C031957PGDB_AS000990View
2D structure for PGDB_C031983
IC50-=52.1nM-—KRASCRBNH358WO2026114958A1PGDB_A002752PGDB_C031983PGDB_AS000990View
2D structure for PGDB_C031979
IC50-=21.6nM-—KRASCRBNH358WO2026114958A1PGDB_A002930PGDB_C031979PGDB_AS000990View
2D structure for PGDB_C031969
IC50-=2.7nM-—KRASCRBNH358WO2026114958A1PGDB_A003618PGDB_C031969PGDB_AS000990View
2D structure for PGDB_C031959
IC50-=8.6nM-—KRASCRBNH358WO2026114958A1PGDB_A003873PGDB_C031959PGDB_AS000990View
2D structure for PGDB_C031981
IC50-=9.3nM-—KRASCRBNH358WO2026114958A1PGDB_A003883PGDB_C031981PGDB_AS000990View
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