Assay

PGDB_AS001328

System: cell_basedTarget: IKZF2Cell line: HEK293T
Assay context summary

Assay context

86 activity records
Assay familycellular_function
Systemcell_based
ReadoutEC50
TargetIKZF2
E3CRBN
Cell lineHEK293T
OrganismHomo sapiens
Technologyfluorescence
Activity compounds and values

Activity records

86 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C000416
EC50-=0.026uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A007974PGDB_C000416PGDB_AS001328View
2D structure for PGDB_C000471
EC50-=0.014uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A008065PGDB_C000471PGDB_AS001328View
2D structure for PGDB_C000432
EC50->10uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A008149PGDB_C000432PGDB_AS001328View
2D structure for PGDB_C000449
EC50->10uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A010176PGDB_C000449PGDB_AS001328View
2D structure for PGDB_C000408
EC50-=0.011uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A010779PGDB_C000408PGDB_AS001328View
2D structure for PGDB_C000462
EC50-=0.006uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A010818PGDB_C000462PGDB_AS001328View
2D structure for PGDB_C000419
EC50-=0.037uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A011234PGDB_C000419PGDB_AS001328View
2D structure for PGDB_C000460
EC50-=0.008uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A011396PGDB_C000460PGDB_AS001328View
2D structure for PGDB_C000402
EC50-=0.011uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A013183PGDB_C000402PGDB_AS001328View
2D structure for PGDB_C000437
EC50->10uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A013506PGDB_C000437PGDB_AS001328View
2D structure for PGDB_C000440
EC50->10uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A014063PGDB_C000440PGDB_AS001328View
2D structure for PGDB_C000409
EC50-=0.015uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A014314PGDB_C000409PGDB_AS001328View
2D structure for PGDB_C000396
EC50-=0.042uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A015449PGDB_C000396PGDB_AS001328View
2D structure for PGDB_C000470
EC50-=0.011uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A016889PGDB_C000470PGDB_AS001328View
2D structure for PGDB_C000452
EC50-=0.019uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A017561PGDB_C000452PGDB_AS001328View
2D structure for PGDB_C000455
EC50-=0.013uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A021009PGDB_C000455PGDB_AS001328View
2D structure for PGDB_C000459
EC50-=0.036uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A021135PGDB_C000459PGDB_AS001328View
2D structure for PGDB_C000447
EC50->10uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A021855PGDB_C000447PGDB_AS001328View
2D structure for PGDB_C000450
EC50-=0.058uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A023606PGDB_C000450PGDB_AS001328View
2D structure for PGDB_C000418
EC50->10uM-—IKZF2CRBNHEK293TAR126418A1PGDB_A025431PGDB_C000418PGDB_AS001328View
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