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Compound
PGDB_C000452
6 activity records3 related patents
2D structure
N#Cc1ccc(C2CN(C3CCCC3Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2)cc1FCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 0.019 | uM | - | — | CRBN | CRBN | - | US20230265071A1 | PGDB_A015259 | PGDB_C000452 | PGDB_AS001482 | View |
| EC50 | - | = | 0.019 | uM | - | — | IKZF2 | CRBN | HEK293T | AR126418A1 | PGDB_A017561 | PGDB_C000452 | PGDB_AS001328 | View |
| % Degradation | - | = | 48.8 | % | 1 uM | 24 h | IKZF2 | CRBN | HEK293T | CN117836288A | PGDB_A032985 | PGDB_C000452 | PGDB_AS002458 | View |
| % Degradation | - | = | 48.8 | % | 1 uM | 24 h | IKZF2 | - | HEK293T | US20230265071A1 | PGDB_A047630 | PGDB_C000452 | PGDB_AS000278 | View |
| % Degradation | - | = | 48.8 | % | 1 uM | 24 h | IKZF2 | CRBN | HEK293T | AR126418A1 | PGDB_A048428 | PGDB_C000452 | PGDB_AS000416 | View |
| EC50 | - | = | 0.019 | uM | - | — | CRBN | CRBN | HEK293T | CN117836288A | PGDB_A064765 | PGDB_C000452 | PGDB_AS001696 | View |