PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

422 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

TargetSMARCA2

E3Not specified

Cell lineHeLa

OrganismHomo sapiens

Technologyluminescence

Activity compounds and values

Activity records

422 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	>	70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A007167	PGDB_C027074	PGDB_AS001988	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A007444	PGDB_C026883	PGDB_AS001988	View
% Degradation	-	>	70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A007459	PGDB_C026977	PGDB_AS001988	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A007783	PGDB_C027234	PGDB_AS001988	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A007870	PGDB_C026949	PGDB_AS001988	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A007969	PGDB_C027223	PGDB_AS001988	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A007989	PGDB_C026925	PGDB_AS001988	View
% Degradation	-	>	70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A008121	PGDB_C027015	PGDB_AS001988	View
% Degradation	-	>	70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A008397	PGDB_C027251	PGDB_AS001988	View
% Degradation	-	>	70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A008402	PGDB_C026988	PGDB_AS001988	View
% Degradation	-	>	70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A008515	PGDB_C027138	PGDB_AS001988	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A008678	PGDB_C027185	PGDB_AS001988	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A009035	PGDB_C027082	PGDB_AS001988	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A009281	PGDB_C027294	PGDB_AS001988	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A009390	PGDB_C026885	PGDB_AS001988	View
% Degradation	-	>	70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A009417	PGDB_C027002	PGDB_AS001988	View
% Degradation	-	<	30	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A010044	PGDB_C026960	PGDB_AS001988	View
% Degradation	-	>	70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A010100	PGDB_C027123	PGDB_AS001988	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A010496	PGDB_C027182	PGDB_AS001988	View
% Degradation	-	=	30-70	%	1 uM	24 h	SMARCA2	-	HeLa	WO2023244806A1	PGDB_A010665	PGDB_C027144	PGDB_AS001988	View

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