PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

69 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

E3CRBN

TechnologyWestern_blot

Detection targetprotein_degradation

Activity compounds and values

Activity records

69 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	=	106.5	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A008745	PGDB_C009131	PGDB_AS002247	View
% Degradation	-	=	91.11	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A010031	PGDB_C009083	PGDB_AS002247	View
% Degradation	-	=	38.07	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A011858	PGDB_C009099	PGDB_AS002247	View
% Degradation	-	=	36.53	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A012112	PGDB_C009075	PGDB_AS002247	View
% Degradation	-	=	103.81	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A012330	PGDB_C009065	PGDB_AS002247	View
% Degradation	-	=	82.18	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A012496	PGDB_C009107	PGDB_AS002247	View
% Degradation	-	=	6.19	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A013324	PGDB_C009072	PGDB_AS002247	View
% Degradation	-	=	153.23	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A014073	PGDB_C009134	PGDB_AS002247	View
% Degradation	-	=	9.54	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A015499	PGDB_C009094	PGDB_AS002247	View
% Degradation	-	=	157.27	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A016051	PGDB_C009118	PGDB_AS002247	View
% Degradation	-	=	43.73	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A016451	PGDB_C009120	PGDB_AS002247	View
% Degradation	-	=	103.59	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A018124	PGDB_C009125	PGDB_AS002247	View
% Degradation	-	=	16.79	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A018835	PGDB_C009069	PGDB_AS002247	View
% Degradation	-	=	11.85	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A019602	PGDB_C009096	PGDB_AS002247	View
% Degradation	-	=	85.35	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A020226	PGDB_C009084	PGDB_AS002247	View
% Degradation	-	=	63.41	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A021773	PGDB_C009117	PGDB_AS002247	View
% Degradation	-	=	15.76	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A022127	PGDB_C009067	PGDB_AS002247	View
% Degradation	-	=	131.39	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A022395	PGDB_C009135	PGDB_AS002247	View
% Degradation	-	=	150.73	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A023761	PGDB_C009133	PGDB_AS002247	View
% Degradation	-	=	151.45	%	Concentration series: 10 nM, 10 uM	-	CRBN	CRBN	-	US20220362229A1	PGDB_A024267	PGDB_C009132	PGDB_AS002247	View

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