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O=C(COc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O)NCCOCCOCCNC(=O)COc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 15.76 | % | Concentration series: 10 nM, 10 uM | - | CRBN | CRBN | - | US20220362229A1 | PGDB_A022127 | PGDB_C009067 | PGDB_AS002247 | View | |
| % Inhibition | - | = | 68.23 | % | 200 uM | - | - | - | - | US20220362229A1 | PGDB_A023577 | PGDB_C009067 | PGDB_AS001773 | View | |
| Kd | - | = | 12.3 | uM | - | — | CRBN | CRBN | - | US20220362229A1 | PGDB_A032196 | PGDB_C009067 | PGDB_AS002291 | View |