Assay

PGDB_AS002359

System: cell_basedTarget: GSPT1Cell line: NB4
Assay context summary

Assay context

32 activity records
Assay family% Degradation
Systemcell_based
ReadoutDC50
TargetGSPT1
E3Not specified
Cell lineNB4
Detection targetprotein_degradation
Activity compounds and values

Activity records

32 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C003340
DC50-=24nM-—GSPT1-NB4WO2025146129A1PGDB_A011485PGDB_C003340PGDB_AS002359View
2D structure for PGDB_C003351
DC50-=55nM-—GSPT1-NB4WO2025146129A1PGDB_A013219PGDB_C003351PGDB_AS002359View
2D structure for PGDB_C003356
DC50-=37nM-—GSPT1-NB4WO2025146129A1PGDB_A014864PGDB_C003356PGDB_AS002359View
2D structure for PGDB_C003335
DC50-=3.7nM-—GSPT1-NB4WO2025146129A1PGDB_A014981PGDB_C003335PGDB_AS002359View
2D structure for PGDB_C003354
DC50-=2nM-—GSPT1-NB4WO2025146129A1PGDB_A017627PGDB_C003354PGDB_AS002359View
2D structure for PGDB_C003355
DC50-=14nM-—GSPT1-NB4WO2025146129A1PGDB_A018863PGDB_C003355PGDB_AS002359View
2D structure for PGDB_C003359
DC50-=1.8nM-—GSPT1-NB4WO2025146129A1PGDB_A020804PGDB_C003359PGDB_AS002359View
2D structure for PGDB_C003349
DC50-=17nM-—GSPT1-NB4WO2025146129A1PGDB_A022189PGDB_C003349PGDB_AS002359View
2D structure for PGDB_C003344
DC50-=93nM-—GSPT1-NB4WO2025146129A1PGDB_A023151PGDB_C003344PGDB_AS002359View
2D structure for PGDB_C003338
DC50-=6.2nM-—GSPT1-NB4WO2025146129A1PGDB_A029550PGDB_C003338PGDB_AS002359View
2D structure for PGDB_C003352
DC50-=13nM-—GSPT1-NB4WO2025146129A1PGDB_A029975PGDB_C003352PGDB_AS002359View
2D structure for PGDB_C003334
DC50-=154nM-—GSPT1-NB4WO2025146129A1PGDB_A030064PGDB_C003334PGDB_AS002359View
2D structure for PGDB_C003363
DC50-=15nM-—GSPT1-NB4WO2025146129A1PGDB_A033137PGDB_C003363PGDB_AS002359View
2D structure for PGDB_C003342
DC50-=45nM-—GSPT1-NB4WO2025146129A1PGDB_A034119PGDB_C003342PGDB_AS002359View
2D structure for PGDB_C003336
DC50-=85nM-—GSPT1-NB4WO2025146129A1PGDB_A035191PGDB_C003336PGDB_AS002359View
2D structure for PGDB_C003345
DC50-=109nM-—GSPT1-NB4WO2025146129A1PGDB_A040583PGDB_C003345PGDB_AS002359View
2D structure for PGDB_C003364
DC50-=5.7nM-—GSPT1-NB4WO2025146129A1PGDB_A047377PGDB_C003364PGDB_AS002359View
2D structure for PGDB_C003333
DC50-=8.7nM-—GSPT1-NB4WO2025146129A1PGDB_A047784PGDB_C003333PGDB_AS002359View
2D structure for PGDB_C003353
DC50-=1nM-—GSPT1-NB4WO2025146129A1PGDB_A047985PGDB_C003353PGDB_AS002359View
2D structure for PGDB_C003361
DC50-=16nM-—GSPT1-NB4WO2025146129A1PGDB_A048518PGDB_C003361PGDB_AS002359View
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