Assay

PGDB_AS002571

System: biochemicalTarget: CRBN
Assay context summary

Assay context

44 activity records
Assay familybinding
Systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN
Technologyfluorescence
Activity compounds and values

Activity records

44 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C001751
IC50->1100nM-—CRBNCRBN-WO2022219412A1PGDB_A010592PGDB_C001751PGDB_AS002571View
2D structure for PGDB_C001759
IC50->1100nM-—CRBNCRBN-WO2022219412A1PGDB_A010868PGDB_C001759PGDB_AS002571View
2D structure for PGDB_C001726
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A011223PGDB_C001726PGDB_AS002571View
2D structure for PGDB_C001773
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A011643PGDB_C001773PGDB_AS002571View
2D structure for PGDB_C001754
IC50->1100nM-—CRBNCRBN-WO2022219412A1PGDB_A011743PGDB_C001754PGDB_AS002571View
2D structure for PGDB_C001765
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A016237PGDB_C001765PGDB_AS002571View
2D structure for PGDB_C001724
IC50-<=500nM-—CRBNCRBN-WO2022219412A1PGDB_A017011PGDB_C001724PGDB_AS002571View
2D structure for PGDB_C001729
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A017567PGDB_C001729PGDB_AS002571View
2D structure for PGDB_C001740
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A017714PGDB_C001740PGDB_AS002571View
2D structure for PGDB_C000482
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A019208PGDB_C000482PGDB_AS002571View
2D structure for PGDB_C001756
IC50->1100nM-—CRBNCRBN-WO2022219412A1PGDB_A021271PGDB_C001756PGDB_AS002571View
2D structure for PGDB_C001763
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A022368PGDB_C001763PGDB_AS002571View
2D structure for PGDB_C001762
IC50-<=500nM-—CRBNCRBN-WO2022219412A1PGDB_A025744PGDB_C001762PGDB_AS002571View
2D structure for PGDB_C001748
IC50-<=500nM-—CRBNCRBN-WO2022219412A1PGDB_A028308PGDB_C001748PGDB_AS002571View
2D structure for PGDB_C001768
IC50-<=500nM-—CRBNCRBN-WO2022219412A1PGDB_A030811PGDB_C001768PGDB_AS002571View
2D structure for PGDB_C001753
IC50->1100nM-—CRBNCRBN-WO2022219412A1PGDB_A032932PGDB_C001753PGDB_AS002571View
2D structure for PGDB_C001755
IC50-<=500nM-—CRBNCRBN-WO2022219412A1PGDB_A035026PGDB_C001755PGDB_AS002571View
2D structure for PGDB_C001774
IC50-<=500nM-—CRBNCRBN-WO2022219412A1PGDB_A036281PGDB_C001774PGDB_AS002571View
2D structure for PGDB_C001770
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A037507PGDB_C001770PGDB_AS002571View
2D structure for PGDB_C001771
IC50->1100nM-—CRBNCRBN-WO2022219412A1PGDB_A040664PGDB_C001771PGDB_AS002571View
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