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Compound
PGDB_C001724
9 activity records1 related patents
2D structure
Cc1ccc(NC(=O)CCc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)cc1ClCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | <= | 500 | nM | - | — | CRBN | CRBN | - | WO2022219412A1 | PGDB_A015055 | PGDB_C001724 | PGDB_AS000438 | View |
| IC50 | - | <= | 500 | nM | - | — | CRBN | CRBN | - | WO2022219412A1 | PGDB_A017011 | PGDB_C001724 | PGDB_AS002571 | View |
| % Degradation | - | < | 20 | % | 30 uM | - | CSNK1A1 | - | - | WO2022219412A1 | PGDB_A029861 | PGDB_C001724 | PGDB_AS000516 | View |
| % Degradation | - | = | 0 | % | 30 uM | - | IKZF3 | - | - | WO2022219412A1 | PGDB_A037027 | PGDB_C001724 | PGDB_AS001625 | View |
| % Degradation | - | = | 0 | % | Concentration series: 30 uM, 3 uM, 0.3 uM | - | IKZF1 | - | - | WO2022219412A1 | PGDB_A039485 | PGDB_C001724 | PGDB_AS002537 | View |
| % Degradation | - | > | 90 | % | 0.3 uM | - | GSPT1 | - | - | WO2022219412A1 | PGDB_A055840 | PGDB_C001724 | PGDB_AS001648 | View |
| IC50 | - | <= | 500 | nM | - | — | CRBN | CRBN | - | WO2022219412A1 | PGDB_A058784 | PGDB_C001724 | PGDB_AS001297 | View |
| % Degradation | - | < | 20 | % | Concentration series: 30 uM, 3 uM, 0.3 uM | - | ZFP91 | - | - | WO2022219412A1 | PGDB_A060216 | PGDB_C001724 | PGDB_AS000241 | View |
| DC50 | - | = | 16 | nM | - | — | - | - | MM.1S | WO2022219412A1 | PGDB_A073356 | PGDB_C001724 | PGDB_AS001567 | View |