Summary
AssigneeF Hoffmann La Roche
Filing years2018-2019
Patents2
Compounds34
Activity records34
Patent families2
Targets2
Assay familiesbinding, degradation
Activity metricsIC50, Kd
Overview

Target distribution and active-compound trend

Target distribution

34 activity records

2 targets

Active compounds by publication year

Distinct compounds linked to assignee patent publications

017342019
Activity compounds and values

Activity records

34 records
Structure
Control
Value
ConcentrationTime
Record IDCompoundAssayDetails
2D structure for PGDB_C007393
Kd-=0.023uM-CRBNCRBN-EP3556760A1PGDB_A009560PGDB_C007393PGDB_AS000988View
2D structure for PGDB_C007385
Kd-=0.017uM-CRBNCRBN-EP3556760A1PGDB_A012816PGDB_C007385PGDB_AS000988View
2D structure for PGDB_C007383
Kd-=0.002uM-CRBNCRBN-EP3556760A1PGDB_A013644PGDB_C007383PGDB_AS000988View
2D structure for PGDB_C007403
Kd-=0.006uM-CRBNCRBN-EP3556760A1PGDB_A016107PGDB_C007403PGDB_AS000988View
2D structure for PGDB_C007404
Kd-=0.006uM-CRBNCRBN-EP3556760A1PGDB_A017791PGDB_C007404PGDB_AS000988View
2D structure for PGDB_C007384
Kd-=0.002uM-CRBNCRBN-EP3556760A1PGDB_A020924PGDB_C007384PGDB_AS000988View
2D structure for PGDB_C025999
Kd-=0.007uM-CRBNCRBN-EP3556760A1PGDB_A024556PGDB_C025999PGDB_AS000988View
2D structure for PGDB_C026003
Kd-<0.001uM-CRBNCRBN-EP3556760A1PGDB_A030028PGDB_C026003PGDB_AS000988View
2D structure for PGDB_C007389
Kd-=0.001uM-CRBNCRBN-EP3556760A1PGDB_A032428PGDB_C007389PGDB_AS000988View
2D structure for PGDB_C026001
Kd-=0.002uM-CRBNCRBN-EP3556760A1PGDB_A036296PGDB_C026001PGDB_AS000988View
2D structure for PGDB_C007391
Kd-=0.016uM-CRBNCRBN-EP3556760A1PGDB_A042542PGDB_C007391PGDB_AS000988View
2D structure for PGDB_C007388
Kd-=0.021uM-CRBNCRBN-EP3556760A1PGDB_A042760PGDB_C007388PGDB_AS000988View
2D structure for PGDB_C007396
Kd-=0.006uM-CRBNCRBN-EP3556760A1PGDB_A043155PGDB_C007396PGDB_AS000988View
2D structure for PGDB_C007402
Kd-=0.028uM-CRBNCRBN-EP3556760A1PGDB_A047173PGDB_C007402PGDB_AS000988View
2D structure for PGDB_C007399
Kd-=0.015uM-CRBNCRBN-EP3556760A1PGDB_A048840PGDB_C007399PGDB_AS000988View
2D structure for PGDB_C007387
Kd-=0.027uM-CRBNCRBN-EP3556760A1PGDB_A057013PGDB_C007387PGDB_AS000988View
2D structure for PGDB_C007400
Kd-=0.006uM-CRBNCRBN-EP3556760A1PGDB_A066296PGDB_C007400PGDB_AS000988View
2D structure for PGDB_C007390
Kd-<0.001uM-CRBNCRBN-EP3556760A1PGDB_A066768PGDB_C007390PGDB_AS000988View
2D structure for PGDB_C007386
Kd-=0.034uM-CRBNCRBN-EP3556760A1PGDB_A068908PGDB_C007386PGDB_AS000988View
2D structure for PGDB_C011112
Kd-=0.011uM-CRBNCRBN-EP3556760A1PGDB_A071403PGDB_C011112PGDB_AS000988View