PatGlueDB | Molecular Glue Patent Bioactivity Database

Activity compounds and values

Activity records

28 records

	Control		Value		Concentration	Time					Record ID	Compound	Assay	Details
IC50	-	=	0.8	nM	-	—	ESR1	-	MCF-7	CN115611909A	PGDB_A008222	PGDB_C006622	PGDB_AS001650	View
IC50	-	=	1.4	nM	-	—	ESR1	-	MCF-7	CN115611909A	PGDB_A008394	PGDB_C006624	PGDB_AS001650	View
IC50	-	=	0.9	nM	-	—	ESR1	-	MCF-7	CN115611909A	PGDB_A011143	PGDB_C006621	PGDB_AS001650	View
IC50	-	=	3.1	nM	-	—	ESR1	-	MCF-7	CN115611909A	PGDB_A011853	PGDB_C006622	PGDB_AS000455	View
IC50	-	=	1.1	nM	-	—	ESR1	-	-	CN115611909A	PGDB_A016128	PGDB_C006623	PGDB_AS002471	View
IC50	-	=	0.5	nM	-	—	ESR1	-	-	CN115611909A	PGDB_A039560	PGDB_C006621	PGDB_AS002471	View
IC50	-	=	1.3	nM	-	—	ESR1	-	-	CN115611909A	PGDB_A042773	PGDB_C006624	PGDB_AS002471	View
IC50	-	=	7.1	nM	-	—	ESR1	-	MCF-7	CN115611909A	PGDB_A048588	PGDB_C006623	PGDB_AS000455	View
IC50	-	=	0.7	nM	-	—	ESR1	-	MCF-7	CN115611909A	PGDB_A052851	PGDB_C006623	PGDB_AS001650	View
IC50	-	=	0.8	nM	-	—	ESR1	-	-	CN115611909A	PGDB_A062118	PGDB_C006622	PGDB_AS002471	View
IC50	-	=	2.4	nM	-	—	ESR1	-	MCF-7	CN115611909A	PGDB_A069913	PGDB_C006621	PGDB_AS000455	View
IC50	-	=	8	nM	-	—	ESR1	-	MCF-7	CN115611909A	PGDB_A072531	PGDB_C006624	PGDB_AS000455	View
% Cell viability	-	=	13	%	-	-	ESR1	-	MCF-7	RU2847441C1	PGDB_A009831	PGDB_C008967	PGDB_AS002582	View
IC50	-	=	0.07	nM	-	—	ESR1	-	MCF-7	RU2847441C1	PGDB_A013222	PGDB_C008966	PGDB_AS001905	View
IC50	-	=	0.2	nM	-	—	ESR1	-	MCF-7	RU2847441C1	PGDB_A021288	PGDB_C008964	PGDB_AS002097	View
% Degradation	-	=	97	%	-	-	ESR1	-	MCF-7	RU2847441C1	PGDB_A025453	PGDB_C008965	PGDB_AS002178	View
IC50	-	=	0.05	nM	-	—	ESR1	-	MCF-7	RU2847441C1	PGDB_A025684	PGDB_C008966	PGDB_AS002097	View
IC50	-	=	0.21	nM	-	—	ESR1	-	MCF-7	RU2847441C1	PGDB_A025938	PGDB_C008964	PGDB_AS001905	View
IC50	-	=	0.3	nM	-	—	ESR1	-	MCF-7	RU2847441C1	PGDB_A035799	PGDB_C008967	PGDB_AS002097	View
% Cell viability	-	=	4	%	-	-	ESR1	-	MCF-7	RU2847441C1	PGDB_A041576	PGDB_C008964	PGDB_AS002582	View

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Jiangsu Hengrui Medicine

Target distribution and active-compound trend

Target distribution

Active compounds by publication year

Activity records