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Compound
PGDB_C000074
6 activity records1 related patents
2D structure
CC(=O)Oc1cc(C)cc(C)c1C(C)(C)CC(=O)NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=OCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | > | 50 | uM | - | — | - | - | H929 | CN116457344A | PGDB_A011855 | PGDB_C000074 | PGDB_AS000797 | View |
| IC50 | - | <= | 0.1 | uM | - | — | - | - | Hep3B | CN116457344A | PGDB_A012141 | PGDB_C000074 | PGDB_AS001471 | View |
| IC50 | - | = | 1-5 | uM | - | — | - | - | KG-1 | CN116457344A | PGDB_A037922 | PGDB_C000074 | PGDB_AS000548 | View |
| IC50 | - | = | 1000-5000 | nM | - | — | - | - | Kelly | CN116457344A | PGDB_A038388 | PGDB_C000074 | PGDB_AS002343 | View |
| Ki | - | < | 0.5 | uM | - | — | CRBN | CRBN | - | CN116457344A | PGDB_A044394 | PGDB_C000074 | PGDB_AS001592 | View |
| % Degradation | - | > | 80 | % | 100 nM | 24 h | SALL4 | - | Kelly | CN116457344A | PGDB_A047425 | PGDB_C000074 | PGDB_AS001684 | View |