Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C000963
9 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(CN4CCC(N5CCN(C(c6ccccc6)c6ccccc6)CC5)C(F)(F)C4)ccc3C2=S)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 30-40 | % | 0.1 uM | 24 h | - | - | - | CN120548310A | PGDB_A010809 | PGDB_C000963 | PGDB_AS000650 | View |
| % Inhibition | - | = | -50-0 | % | 0.1 uM | 24 h | - | - | - | CN120548310A | PGDB_A019263 | PGDB_C000963 | PGDB_AS000584 | View |
| % Inhibition | - | = | -50-0 | % | 0.1 uM | 24 h | - | - | - | CN120548310A | PGDB_A035377 | PGDB_C000963 | PGDB_AS001714 | View |
| % Inhibition | - | = | 80-90 | % | 1 uM | 24 h | - | - | - | CN120548310A | PGDB_A036058 | PGDB_C000963 | PGDB_AS001951 | View |
| % Inhibition | - | = | 40-50 | % | 1 uM | 24 h | - | - | - | CN120548310A | PGDB_A041250 | PGDB_C000963 | PGDB_AS000125 | View |
| % Inhibition | - | = | 90-100 | % | 1 uM | 24 h | - | - | - | CN120548310A | PGDB_A048979 | PGDB_C000963 | PGDB_AS000346 | View |
| IC50 | - | <= | 0.1 | uM | - | — | CRBN | CRBN | - | CN120548310A | PGDB_A062716 | PGDB_C000963 | PGDB_AS000323 | View |
| % Inhibition | - | = | 70-80 | % | 1 uM | 24 h | - | - | - | CN120548310A | PGDB_A064659 | PGDB_C000963 | PGDB_AS000296 | View |
| % Inhibition | - | = | 40-50 | % | 0.1 uM | 24 h | IL1B | - | - | CN120548310A | PGDB_A073043 | PGDB_C000963 | PGDB_AS002470 | View |